Comparison between solution-phase stability and gas-phase kinetic stability of oligodeoxynucleotide duplexes
نویسندگان
چکیده
منابع مشابه
Comparison between solution-phase stability and gas-phase kinetic stability of oligodeoxynucleotide duplexes.
The relative kinetic stabilities of different 16-mer oligonucleotide duplexes were investigated by source collision-induced dissociation (CID) in a heated capillary electrospray ion source. They were compared with the relative stabilities in solution obtained by thermal denaturation monitored by UV spectrophotometry. The results clearly show that both hydrogen bonding and base stacking interact...
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ژورنال
عنوان ژورنال: Journal of Mass Spectrometry
سال: 2001
ISSN: 1076-5174,1096-9888
DOI: 10.1002/jms.141